Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
CA-074 has been used as a cathepsin B inhibitor:to study its effect on pseudotyped viruses bearing S proteins harboring R642M and N714K using HeLa cellsto determine the role of autophagy in glucose deprivation (GD)-induced damageto study its effects on neuronal function upon exposure to His-cathepsin B (CATB)
Biochem/physiol Actions
CA-074 is a potent and a selective inhibitor of cathepsin B. It is useful to study the biological function of cathepsin B in vivo. Studies show that CA-074 can also inhibit cathepsin L under reducing conditions.
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