CA-074, >=99% (TLC)

Code: C5732-5MG D2-231

Not available outside of the UK & Ireland.

Application

CA-074 has been used as a cathepsin B inhibitor:to study its effect on pseudotyped viruses bearing S proteins harboring R642M and N714K using HeLa cellsto determi...


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$582.38 5MG
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Not available outside of the UK & Ireland.

Application

CA-074 has been used as a cathepsin B inhibitor:to study its effect on pseudotyped viruses bearing S proteins harboring R642M and N714K using HeLa cellsto determine the role of autophagy in glucose deprivation (GD)-induced damageto study its effects on neuronal function upon exposure to His-cathepsin B (CATB)

Biochem/physiol Actions

CA-074 is a potent and a selective inhibitor of cathepsin B. It is useful to study the biological function of cathepsin B in vivo. Studies show that CA-074 can also inhibit cathepsin L under reducing conditions.

assay≥99% (TLC)
biological sourcesynthetic (organic)
formpowder
InChI keyZEZGJKSEBRELAS-NSIINPIOSA-N
InChI1S/C18H29N3O6/c1-4-8-19-15(22)13-14(27-13)16(23)20-12(10(3)5-2)17(24)21-9-6-7-11(21)18(25)26/h10-14H,4-9H2,1-3H3,(H,19,22)(H,20,23)(H,25,26)/t10?,11-,12-,13-,14-/m0/s1
Quality Level200
SMILES stringCCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H]([C@H](C)CC)C(=O)N2CCC[C@H]2C(O)=O
solubilitymethanol: 1 mg/mL, clear, colorless
storage temp.−20°C
Cas Number134448-10-5
This product has met the following criteria to qualify for the following awards:



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