Anti-CLDN1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Claudin 1 (CLDN1) has a role in epithelial-mesenchymal transition. It is a sealing and tightening junctional protein. CLDN1 has been shown to be downregulated in lung adenocarcinoma. Mutations in this gene have also been linked to neonatal ichthyosis and sclerosing cholangitis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Claudin 1 (CLDN1) is a component of tight junctions. It is part of the transmembrane tight junction protein family. The CLDN1 gene is localized on human chromosome 3q28.

Immunogen

CLDN1 antibody was raised against a 20 amino acid peptide near the carboxyl terminus of human CLDN1.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500438.

Physical form

Supplied in PBS with 0.02% sodium azide.