Anticorps Anti - CLDN1 produit dans le lapin, anticorps isolé affinité, solution aqueuse tamponnée

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

Claudin 1 (CLDN1) has a role in epithelial-mesenchymal transition. It is a sealing and tightening junctional protein. CLDN1 has been shown to be downregulated in lung adenocarcinoma. Mutations in this gene have also been linked to neonatal ichthyosis and sclerosing cholangitis.

Features and Benefits

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General description

Claudin 1 (CLDN1) is a component of tight junctions. It is part of the transmembrane tight junction protein family. The CLDN1 gene is localized on human chromosome 3q28.

Immunogen

CLDN1 antibody was raised against a 20 amino acid peptide near the carboxyl terminus of human CLDN1.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500438.

Physical form

Supplied in PBS with 0.02% sodium azide.