Activins are members of the transforming growth factor-beta (TGF-β) superfamily, a group of proteins that play key roles in regulating cell growth, survival and differentiation. In vivo activins exist as homodimers or heterodimers, the activin heterodimer AB is widely expressed and biologically active with similar functions to the activin AA homodimer. Qkine recombinant activin AB is a bioactive 25.7 kDa heterodimer, animal origin-free, tag free and carrier free for improved reproducibility.
- High purity human Activin AB protein (UniProt: P08476 and P09529)
- 25.7kDa (dimer)
- ﹥98%, by SDS-PAGE quantitative densitometry
- Animal origin-free (AOF) and carrier protein-free
- Expressed in E. coli
- Manufactured in Cambridge, UK laboratories
- Lyophilised from acetonitrile, TFA
- Featured applications: drug discovery in metabolism, wound healing and fibrosis
- Alternative names: ActA, Activin beta-A chain, Erythroid differentiation protein (EDP), Follicle-Stimulating Hormone (FSH) releasing protein (FRP), INHBA, Inhibin beta A, Inhibin beta 1, ActB, Activin beta-B chain, INHBB, Inhibin beta B, Inhibin beta 2, Inhibin Subunit Beta B, Inhibin Beta B Chain, Activin Beta-B Chain, Inhibin, Beta B (Activin AB Beta Polypeptide), activin AB Beta Polypeptide, Inhibin Beta B Subunit, Inhibin, Beta B, Inhibin, Beta-2
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