Growth differentiation factor -11 (GDF-11) also known as bone morphogenetic protein 11 (BMP-11) is a member of the transforming growth factor-beta (TGF-β) superfamily, a group of proteins that play key roles in regulating cell growth, survival and differentiation. GDF-11 plays a key role in cardiac and neuronal development. Qkine recombinant GDF-11 (BMP-11) is provided as a pure 25 kDa dimer with high and consistent bioactivity lot-to-lot.
- High purity human protein (UniProt: H0YI30)
- 25kDa (dimer)
- ﹥98%, by SDS-PAGE quantitative densitometry
- Expressed in E. coli
- Animal origin-free (AOF) and carrier protein-free
- Manufactured in ISO 9001:2015 facility in Cambridge, UK
- Lyophilised from acetonitrile
- Resuspend in 10mM HCl (reconstitution solution A) at ﹥50µg/mL, add carrier protein if desired, prepare single-use aliquots and store frozen at -20°C (short-term) or -80°C (long-term)
- Featured applications: neurogenesis and neural differentiation, wound healing and tissue repair
- Alternative names: Growth Differentiation Factor 11, GDF11, BMP11, Bone Morphogenetic Protein 11, VHO
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