Phosgene solution, 15 wt. % in toluene

Not available outside of the UK & Ireland.

Application

Phosgene solution may be used in the synthesis of:sulfonyl chloridesFmoc (Fluorenylmethyloxycarbonyl chloride)-taurylsulfonyl chlorideO-benzyl-L-serine carboxyanhydrides

Phosgene solution (15 wt. % in toluene) has been used to synthesize the following peptide monomers:γ-(4-propargyloxybenzyl)-L-glutamic acid N-carboxyanhydride (POB-L-Glu-NCA)γ-(4,5-dimethoxy-2-nitrobenzyl)-L-glutamate N-carboxyanhydride (DMNB-L-Glu-NCA)γ-(4,5-dimethoxy-2-nitrobenzyl)-D-glutamate N-carboxyanhydride (DMNB-D-Glu-NCA)2-nitrobenzyl(4-vinylphenyl)carbamate

General description

Phosgene is formed during the free radical induced degradation of chlorinated hydrocarbons. Determination of phosgene in air samples using thermal desorption (TD) followed by gas chromatography-mass spectrometry (GC-MS) has been reported.

Legal Information

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Packaging

4×25, 100 mL in Sure/Seal™

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.