Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC columns deliver high-resolution, reproducible separations for monoclonal antibodies, antibody subunits, and ADCs across development and QC workflows. Built on monodisperse, supermacroporous polymeric particle technology with bio-inert hardware, they provide stable performance under elevated temperatures used in LC-MS, enabling consistent peak shape, reliable resolution, and durable operation for scalable protein analysis.
- Designed for reversed-phase protein separations
- Engineered for intact proteins, mAbs and ADCs, delivering reliable retention and selectivity across a wide range of molecular weights
- Bioinert, metal-free flow path
- Optimized for LC-MS protein workflows
- Fully compatible with MS-friendly mobile phases, enabling sensitive and reproducible detection of intact proteins and peptide maps
- Robust stationary phase for high-temperature operation
- Maintains stable performance under elevated temperatures and high organic conditions, supporting fast gradients and durable methods
- Delivers sharp, symmetrical peaks and effective separation of protein variants, isoforms, and closely related species
- Tight manufacturing controls ensure consistent results and smooth method transfer between instruments and laboratories
- Supports method development, characterization, and QC workflows, reducing the need for multiple column chemistries.
- Compatible with UHPLC and HPLC systems
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