Thiamphenicol,

Code: T0261-25G D2-231

Not available outside of the UK & Ireland.

Application

Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at t...


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$741.76 25G
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Not available outside of the UK & Ireland.

Application

Thiamphenicol is an antibiotic that has been used to treat chancroid in men and uncomplicated gonorrhea. It is used in studies of bacterial protein synthesis at the level of peptidyl transferase activity associated with the 23S rRNA of the 50S ribosomal subunit. It is used to study chloraniphenicol-thiamphenicol-resistance and the use of fluorinated analogs when resistance is encountered.

Biochem/physiol Actions

Thiamphenicol inhibits mitochondrial protein synthesis of proteins such as cytochrome c oxidase.

General description

Chemical structure: phenicole

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

1G,5G,25G

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria
colorwhite to off-white
formpowder
InChI keyOTVAEFIXJLOWRX-NXEZZACHSA-N
InChI1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
mode of actionprotein synthesis | interferes
Quality Level100
SMILES stringCS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl
solubilityethanol: soluble 50 mg/mL
Cas Number15318-45-3
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