Dehydroabietic acid, >=95% (LC/MS-ELSD)

Not available outside of the UK & Ireland.

Application

Dehydroabietic acid has been used as a reference standard:to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR)to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopyto estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis

Biochem/physiol Actions

Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects.

General description

Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA).