Er-27319

Code: e0656-25mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

ER-27319 inhibits Syk activation with an IC50 = 10 μM. ER-27319 inhibits Syk by preventing the phosphorylated ITAM domain of FcεRI γ from a...


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Your Price
$1,283.50 25MG
Discontinued

Not available outside of the UK & Ireland.

Biochem/physiol Actions

ER-27319 inhibits Syk activation with an IC50 = 10 μM. ER-27319 inhibits Syk by preventing the phosphorylated ITAM domain of FcεRI γ from activating Syk. ER-27319 does NOT inhibit previously activated Syk.

Selective Syk inhibitor. Induces tyrosine phosphorylation of Syk that has been demonstrated as critical for degranulation.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5 mg in glass bottle

25 mg in poly bottle

assay≥98% (HPLC)
formsolid
InChI keyIIELZHYJYZBSGG-UHFFFAOYSA-N
InChI1S/C18H20N2O.C2H2O4/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21;3-1(4)2(5)6/h3-4,6-9H,5,10-11,19H2,1-2H3;(H,3,4)(H,5,6)
Quality Level100
SMILES stringOC(=O)C(O)=O.Cc1ccc2C(=O)c3ccccc3N(CCCN)c2c1C
solubilityDMSO: 28 mg/mL
storage temp.2-8°C
Cas Number0201010-95-9
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