ER-27319,> = 98 %( HPLC), solide

Name: ER-27319,> = 98 %( HPLC), solide
Brand: SIGMA-ALDRICH
SKU: e0656-25mg
Price: 1283.50 USD

Code: e0656-25mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

ER-27319 inhibits Syk activation with an IC₅₀ = 10 μM. ER-27319 inhibits Syk by preventing the phosphorylated ITAM domain of FcεRI γ from a...

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$1,283.50 25MG

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DOCUMENTS
ATTRIBUTS

Non disponible en dehors du Royaume-Uni et de l'Irlande

Biochem/physiol Actions

ER-27319 inhibits Syk activation with an IC₅₀ = 10 μM. ER-27319 inhibits Syk by preventing the phosphorylated ITAM domain of FcεRI γ from activating Syk. ER-27319 does NOT inhibit previously activated Syk.

Selective Syk inhibitor. Induces tyrosine phosphorylation of Syk that has been demonstrated as critical for degranulation.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5 mg in glass bottle

25 mg in poly bottle

assay	≥98% (HPLC)
form	solid
InChI key	IIELZHYJYZBSGG-UHFFFAOYSA-N
InChI	1S/C18H20N2O.C2H2O4/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21;3-1(4)2(5)6/h3-4,6-9H,5,10-11,19H2,1-2H3;(H,3,4)(H,5,6)
Quality Level	100
SMILES string	OC(=O)C(O)=O.Cc1ccc2C(=O)c3ccccc3N(CCCN)c2c1C
solubility	DMSO: 28 mg/mL
storage temp.	2-8°C

Safety Data Sheet for E0656-25MG
Certificat d'analyse Sigma

Cas Number

0201010-95-9

Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :

ER-27319,> = 98 %( HPLC), solide

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