WS-12, >=98% (HPLC), powder

Code: W0519-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

WS-12 is a high-affinity, selective TRPM8 (cold menthol receptor 1; CMR1) agonist. TRPM8 agonists induce a cooling sensation in sensory neurons and pr...


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$249.05 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

WS-12 is a high-affinity, selective TRPM8 (cold menthol receptor 1; CMR1) agonist. TRPM8 agonists induce a cooling sensation in sensory neurons and produce profound, mechanistically novel analgesia in chronic pain states such as neuropathic pain.

WS-12 is a menthol derivative, that shows a specific binding affinity towards TRPM8 (transient receptor potential cation channel subfamily M member 8) receptor. TRPM8 is associated with prostate cancer and thus, WS-12 might be useful in reducing the progression of cancer.

Packaging

5 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formpowder
InChI keyHNSGVPAAXJJOPQ-NVPAJSRCSA-N
InChI1S/C18H27NO2/c1-12(2)16-10-5-13(3)11-17(16)18(20)19-14-6-8-15(21-4)9-7-14/h6-9,12-13,16-17H,5,10-11H2,1-4H3,(H,19,20)/t13-,16?,17?/m1/s1
Quality Level100
SMILES stringCOc1ccc(NC(=O)C2C[C@H](C)CC[C@H]2C(C)C)cc1
solubilityDMSO: >20 mg/mL
storage temp.−20°C
Cas Number68489-09-8
This product has met the following criteria to qualify for the following awards:



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