Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
CYP2E1 & 1A2 metabolite of chlorzoxazone.
6-hydroxy Chlorzoxazone has been used: as a reference standard to monitor substrate depletion or 6-hydroxy chlorzoxazone formation by cytochrome P450 family 2 subfamily E member 1 (CYP2E1)in recombinant human enzyme screening. 6-Hydroxychlorzoxazone has been used for high-performance liquid chromatography (HPLC)-based metabolic assays of chlorzoxazone.
6-Hydroxychlorzoxazone has been used for HPLC-based metabolic assays of chlorzoxazone.
Biochem/physiol Actions
6-hydroxy Chlorzoxazone is a novel metabolite of chlorzoxazone. It is formed by the hydroxylation of chlorzoxazone by cytochrome P450 family 2 subfamily E member 1 (CYP2E1) enzyme. The determination of formation and clearance of 6-hydroxychlorzoxazone is used as a reliable marker of CYP2E1 metabolic activity.
Packaging
5, 10 mg in glass bottle
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
6-Hydroxychlorzoxazone is soluble in methanol.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :