Torsemide, >=98% (HPLC), solid

Not available outside of the UK & Ireland.

Application

Torsemide has been used as an inhibitor of Na⁺ Cl^- co-transporter in transgenic Arabidopsis thaliana plants¹.

Biochem/physiol Actions

Torsemide functions in the thick ascending limb of the loop of Henle and enhances the excretion of sodium, chloride and water from the luminal side of the cells. Furthermore, torsemide can treat oedematous conditions that are associated with diseases such as liver cirrhosis, kidney disorders and chronic congestive heart failure².

Torsemide is a loop diuretic of the pyridine-sulfonylurea class with antialdosteronergic properties and inhibitor of the Na⁺/K⁺/2Cl^- carrier system.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T3202.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Packaging

10, 50 mg in glass bottle

Preparation Note

Torsemide is soluble in DMSO at 18 mg/ml and is insoluble in water.