CHR-6494 trifluoroacetate salt, >=98% (HPLC)

Code: SML0648-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. CHR-6494 c...


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Your Price
$121.29 5MG

Not available outside of the UK & Ireland.

Biochem/physiol Actions

CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. CHR-6494 causes cell cycle arrest in G2/M and subsequent apoptosis. CHR-6494 causes an abnormal duplication of centrosomes and mitotic catastrophe in cancer cells.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyILWYDZNXJQESDI-UHFFFAOYSA-N
InChI1S/C16H16N6.C2HF3O2/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13;3-2(4,5)1(6)7/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20);(H,6,7)
Quality Level100
SMILES stringOC(=O)C(F)(F)F.CCCNc1ccc2ncc(-c3ccc4[nH]ncc4c3)n2n1
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
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