BRD4770, >=98% (HPLC)

Code: SML0567-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

BRD4770 is a selective inhibitor of the histone methyltransferase G9a. BRD4770 blocks lysine residue 9 methylation of histone H3 without inducing apop...


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$149.43 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

BRD4770 is a selective inhibitor of the histone methyltransferase G9a. BRD4770 blocks lysine residue 9 methylation of histone H3 without inducing apoptosis. In PANC-1 cells, BRD4770 activates the ataxia telangiectasia mutated (ATM) pathway, induces senescence and inhibits anchorage-dependent and -independent growth.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyUCGWYCMPZXDHNR-UHFFFAOYSA-N
InChI1S/C25H23N3O3/c1-31-24(30)20-14-15-22-21(17-20)26-25(27-23(29)19-12-6-3-7-13-19)28(22)16-8-11-18-9-4-2-5-10-18/h2-7,9-10,12-15,17H,8,11,16H2,1H3,(H,26,27,29)
Quality Level100
SMILES stringO=C(C1=CC=CC=C1)NC2=NC3=C(N2CCCC4=CC=CC=C4)C=CC(C(OC)=O)=C3
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number1374601-40-7
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