MK-0343, >=98% (HPLC)

Code: SML0565-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

MK-0343 (MRK-409) is a partial agonist for GABAA receptors with comparable Ki values for α1, α2, α3 and α5 containing receptors (0...


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$441.55 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

MK-0343 (MRK-409) is a partial agonist for GABAA receptors with comparable Ki values for α1, α2, α3 and α5 containing receptors (0.2 – 0.4 nM). The compound has the greatest agonist activity against α3 receptors, and is brain penatrant, and displays anxiolytic activity in rodent and primate models.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyGOIFCXRIFSYPFG-UHFFFAOYSA-N
InChI1S/C19H17F2N7O/c1-27-16(22-10-23-27)9-29-19-12(11-4-2-5-11)8-15-24-25-18(28(15)26-19)17-13(20)6-3-7-14(17)21/h3,6-8,10-11H,2,4-5,9H2,1H3
Quality Level100
SMILES stringCn1ncnc1COc2nn3c(nnc3cc2C4CCC4)-c5c(F)cccc5F
solubilityDMSO: 10 mg/mL, clear
storage temp.2-8°C
Cas Number233275-76-8
This product has met the following criteria to qualify for the following awards:



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