BETP, >=98% (HPLC)

Code: SML0558-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

BetP is a trimeric Na+-coupled betaine symporter. BetP belongs to the betaine-choline-carnitine transporter (BCCT) family. It controls tran...


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$534.44 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

BetP is a trimeric Na+-coupled betaine symporter. BetP belongs to the betaine-choline-carnitine transporter (BCCT) family. It controls transport activity in dependence of the cytoplasmic K+-concentration.

BETP is a positive allosteric modulator of the GLP-1 receptor that potentiates cAMP accumulation and glucose-dependent insulin release in pancreatic islet cells, in the presence of the weak GLP-1 metabolite, GLP-1(9-36). BETP has additive effects on the endogenous GLP-1 receptor ligand GLP-1(7-36).

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyNTDFYGSSDDMNHI-UHFFFAOYSA-N
InChI1S/C20H17F3N2O2S/c1-2-28(26)19-24-17(12-18(25-19)20(21,22)23)15-9-6-10-16(11-15)27-13-14-7-4-3-5-8-14/h3-12H,2,13H2,1H3
Quality Level100
SMILES stringCCS(=O)c1nc(cc(n1)C(F)(F)F)-c2cccc(OCc3ccccc3)c2
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number1371569-69-5
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