VU0361737, >=98% (HPLC)

Code: SML0494-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50

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$298.86 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formfilm
InChI keyARYUXFNGXHNNDM-UHFFFAOYSA-N
InChI1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
Quality Level100
SMILES stringCOc1cc(NC(=O)c2ccccn2)ccc1Cl
solubilityDMSO: 15 mg/mL (clear solution)
storage temp.2-8°C
Cas Number1161205-04-4
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