SB-268262, >=98% (HPLC)

Code: SML0391-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP binding, and CGRP-mediated stimulation of adenylyl cycl...


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$391.74 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP binding, and CGRP-mediated stimulation of adenylyl cyclase activity in human neuroblastoma cells with IC50 values of 240 and 830 nM, respectively.

Features and Benefits

This compound is featured on the Calcitonin Gene-Related Peptides page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyYXHLPJQQPOMPGE-UHFFFAOYSA-N
InChI1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3
Quality Level100
SMILES stringCN(C(=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)c2nccs2)c3ccccc3C
solubilityDMSO: >5 mg/mL
storage temp.2-8°C
Cas Number217438-17-0
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