A 887826, >=98% (HPLC)

Code: SML0345-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

A-887826 is Nav1.8 channel blocker (IC50 = 11 nM) that blocks TTX-resistant sodium currents in rat dorsal root ganglion in a voltage depend...


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$617.91 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

A-887826 is Nav1.8 channel blocker (IC50 = 11 nM) that blocks TTX-resistant sodium currents in rat dorsal root ganglion in a voltage dependent fashion. Oral administration of A-887826 to rats significantly attenuated tactile allodynia in a neuropathic pain model.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyJPJGFWKHSMUKFO-UHFFFAOYSA-N
InChI1S/C26H29ClN4O3/c1-2-3-11-34-24-7-6-19(15-23(24)27)21-14-22(17-28-16-21)26(32)30-18-20-5-4-8-29-25(20)31-9-12-33-13-10-31/h4-8,14-17H,2-3,9-13,18H2,1H3,(H,30,32)
Quality Level100
SMILES stringCCCCOc1ccc(cc1Cl)-c2cncc(c2)C(=O)NCc3cccnc3N4CCOCC4
solubilityDMSO: ≥5 mg/mL
storage temp.2-8°C
Cas Number1266212-81-0
Hazard Class6.1
Un Number2811
Pack Group3
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