SR 59230A, >=98% (HPLC), powder

Code: S8688-5MG D2-231

Not available outside of the UK & Ireland.

Application

SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac fun...


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$216.74 5MG
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Not available outside of the UK & Ireland.

Application

SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac function in rat model of heart failure.4

Biochem/physiol Actions

SR 59230A is a β3-adrenoceptor antagonist. It has high affinity for the β3 adrenoceptors occurring in human gut that affect the function of human colonic circular smooth muscle.1 It is reported that SR 59230A inhibits the Kir2.1-2.3 cardiac potassium channels.2

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... ADRB3(155)
InChI keyXTBQNQMNFXNGLR-MKSBGGEFSA-N
InChI1S/C21H27NO2.C2H2O4/c1-2-16-8-4-6-13-21(16)24-15-18(23)14-22-20-12-7-10-17-9-3-5-11-19(17)20;3-1(4)2(5)6/h3-6,8-9,11,13,18,20,22-23H,2,7,10,12,14-15H2,1H3;(H,3,4)(H,5,6)/t18-,20-;/m0./s1
originatorSanofi Aventis
Quality Level100
SMILES stringOC(=O)C(O)=O.CCc1ccccc1OC[C@@H](O)CN[C@H]2CCCc3ccccc23
solubilityDMSO: >10 mg/mL, H2O: insoluble
Cas Number174689-39-5
This product has met the following criteria to qualify for the following awards:



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