Not available outside of the UK & Ireland.
Application
SB 205384 was used to study GABA-gated currents in rat locus coeruleus neurons.6
Biochem/physiol Actions
SB 205384 is a selective and positive allosteric modulator of non-benzodiazepine site of the GABAA receptor.3 It affects the extrasynaptic GABAA receptors in rat cortical neurons4 and enhances the GABAergic transmission onto pro-opiomelanocortin neurons in mice.5
GABAA receptor modulator selective for the α3β2γ2 subunit combination.
Legal Information
Manufactured and sold under license from GlaxoSmithKline Pharmaceuticals
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