SB-269970 hydrochloride, powder, >=98% (HPLC)

Code: S7389-25MG D2-231

Not available outside of the UK & Ireland.

Application

SB-269970 hydrochloride has been used to study the effect of different endotype combination on the activity of the 5-hydroxytryptamine receptor of tall fescue alk...


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Your Price
$1,426.97 25MG
REQUEST

Not available outside of the UK & Ireland.

Application

SB-269970 hydrochloride has been used to study the effect of different endotype combination on the activity of the 5-hydroxytryptamine receptor of tall fescue alkaloids. It has also been used to inhibit dopamine receptor signaling, in order to study its role in early hemocyte activation.

SB-269970 was used to study the role of 5-HT7 receptors in serotonin-induced hypothermia in rodents.6

Biochem/physiol Actions

Selective 5-HT7 serotonin receptor antagonist.

SB-269970 is an anti-psychotic agent that shows high affinity for 5-HT7 receptors. It may be effective in treating cognitive disabilities and schizophrenia-like deficits.4 SB-269970 desensitizes and decreases the excitatory effects of 5-HT7 receptors in rat hippocampus.5

Legal Information

Sold with the permission of GlaxoSmithKline Pharmaceuticals

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
formpowder
Gene Informationhuman ... HTR7(3363)
InChI keyXQCJOYZLWFNDIO-PKLMIRHRSA-N
InChI1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18;/h2,5-6,14-16,21H,3-4,7-13H2,1H3;1H/t16-;/m1./s1
optical activity[α]/D 75 to 90°, c = 1.0 in DMSO
Quality Level100
SMILES stringCl.CC1CCN(CC1)CC[C@H]2CCCN2S(=O)(=O)c3cccc(O)c3
solubilityH2O: 10 mg/mL, clear (warmed to 60 °C)
storage conditiondesiccated
storage temp.2-8°C
Cas Number261901-57-9
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