Streptonigrin from Streptomyces flocculus, >=98%

Code: S1014-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Streptonigrin (SN) is an aminoquinone antitumour antibiotic. Its antineoplastic activity requires reductive activation by Xanthine-converting enzymes....


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$616.56 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Streptonigrin (SN) is an aminoquinone antitumour antibiotic. Its antineoplastic activity requires reductive activation by Xanthine-converting enzymes. It induces apoptosis by a mechanism involving NF-κB. DNA cleavage reaction and chromosome damage by SN are influenced by the nature of the metal ion present and dependent on the production of free radicals. Its antibiotic activity is iron-activated.

antibiotic activity spectrumviruses
assay≥98%
InChI keyPVYJZLYGTZKPJE-UHFFFAOYSA-N
InChI1S/C25H22N4O8/c1-9-14(10-6-8-13(35-2)23(36-3)20(10)30)15(26)19(29-17(9)25(33)34)12-7-5-11-18(28-12)22(32)16(27)24(37-4)21(11)31/h5-8,30H,26-27H2,1-4H3,(H,33,34)
mode of actionDNA synthesis | interferes
Quality Level200
SMILES stringCOc1ccc(c(O)c1OC)-c2c(C)c(nc(c2N)-c3ccc4C(=O)C(OC)=C(N)C(=O)c4n3)C(O)=O
storage temp.2-8°C
Cas Number3930-19-6
Hazard Class6.1
Un Number3462
Pack Group1
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