Midostaurin hydrate, >=98% (HPLC), solid

Code: M1323-1MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Midostaurin is an inhibitor of tyrosine kinase, protein kinase C, and VEGF. Midostaurin inhibits cell growth and phosphorylation of FLT3, STAT5, and E...


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$119.68 1MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Midostaurin is an inhibitor of tyrosine kinase, protein kinase C, and VEGF. Midostaurin inhibits cell growth and phosphorylation of FLT3, STAT5, and ERK. Midostaurin is a potent inhibitor of a spectrum of FLT3 activation loop mutations.

Features and Benefits

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
coloroff-white
formsolid
InChI keyYEKDLUZCCDJYAJ-LJAYRLSQSA-N
InChI1S/C35H30N4O4.H2O/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38;/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40);1H2/t25-,26-,32-,35+;/m1./s1
Quality Level100
SMILES stringO.CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)[n@@H]3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8[n@H]2c7c35)N(C)C(=O)c9ccccc9
solubilityDMSO: >10 mg/mL
storage temp.−20°C
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