Dihydrocapsaicine, de Capsicum sp. , environ 90 %

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Dihydrocapsaicin has been used: as a standard to analyze the level of dihydrocapsaicin in endogenousAn2andcapsaicin synthase silenced fruitsas an external standard to determine the variability in capsaicinoid content in different landraces of capsicumin the activation or ablation of capsaicin-sensitive primary afferents (CSPA) fibres

Biochem/physiol Actions

VR1 vanilloid receptor agonist.

Dihydrocapsaicin/8-methyl-N-vanillylnonanamide; N-[−4-hydroxy-3-methoxybenzyl] 8-methylnonanamide (DHC) is an active component of capsaicinoids in chili peppers. DHC is capable of reducing body temperature. Hence it is considered as a pharmaceutical-induced hypothermia (PIH) candidate to treat cardiac arrest (CA) patients. It may possess anti-cancer, anti-inflammation, antioxidant, anti-obesity properties. DHC might help in the reduction of oxidative stress and inflammation in ischemia and reperfusion (I/R) injury. DHC can repress nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway.

Linkage

Capsaicin analog.

Packaging

1 g in glass bottle

50 mg in poly bottle

250 mg in glass bottle