K 858, >=98% (HPLC)

Code: K3644-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Eg5 is a key protein involved in the formation of bipolar spindles. K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor. The compound ...


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$347.32 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Eg5 is a key protein involved in the formation of bipolar spindles. K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor. The compound induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formpowder
InChI keyJEFVYQYZCAVNTP-UHFFFAOYSA-N
InChI1S/C13H15N3O2S/c1-9(17)14-12-15-16(10(2)18)13(3,19-12)11-7-5-4-6-8-11/h4-8H,1-3H3,(H,14,15,17)
Quality Level100
SMILES stringCC(=O)NC1=NN(C(C)=O)C(C)(S1)c2ccccc2
solubilityDMSO: ≥20 mg/mL
storage temp.2-8°C
Cas Number0072926-24-0
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