ITX3, >=98% (HPLC)

Name: ITX3, >=98% (HPLC)
Brand: SIGMA-ALDRICH
SKU: I1411-5MG
Price: 104.55 USD

Code: I1411-5MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. ...

Your Price

$104.55 5MG

Discontinued

OVERVIEW

Not available outside of the UK & Ireland.

Biochem/physiol Actions

ITX3 is a specific inhibitor of endogenous TrioN activity acting on the GEF domain and selective cell active inhibitor of the Trio/RhoG/Rac1 pathway. The compound is active in whole cell assay where it inhibits the formation of TrioN-dependent cell structures. ITX3 appears to be specific for TrioN inhibition rather than other RhoGEFs.

Features and Benefits

This compound is featured on the GTP Binding Proteins (Low Molecular Weight) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

SPECIFICATIONS

assay	≥98% (HPLC)
form	powder
InChI key	SJMYMKPBODEZSH-DEDYPNTBSA-N
InChI	1S/C22H17N3OS/c1-14-12-16(15(2)24(14)17-8-4-3-5-9-17)13-20-21(26)25-19-11-7-6-10-18(19)23-22(25)27-20/h3-13H,1-2H3/b20-13+
Quality Level	100
SMILES string	Cc1cc(C=C2Sc3nc4ccccc4n3C2=O)c(C)n1-c5ccccc5
solubility	DMSO: ≥4 mg/mL
storage temp.	room temp