5HPP-33, >=98% (HPLC), solid

Code: H9415-25MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown i...


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$522.33 25MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown inhibition of cell proliferation of both estrogen-dependent (MCF-7) and estrogen-independent (MDA-MB-231) breast cancer cells as well as other cell lines. A study in tubulin forming assay reported that 5HPP-33 acts as a microtubule formation inhibitor (IC50=810 nM).

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formsolid
InChI keyLAKWINYVWJPHQW-UHFFFAOYSA-N
InChI1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3
Quality Level100
SMILES stringCC(C)c1cccc(C(C)C)c1N2C(=O)c3ccc(O)cc3C2=O
solubilityDMSO: >20 mg/mL
storage temp.2-8°C
Cas Number105624-86-0
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