Non disponible en dehors du Royaume-Uni et de l'Irlande
Application
Hyperforin may be used:as a reference standard for calibration curve generation in high-perfornamce liquid chromatography (HPLC) analysisto test its cytotoxic effect and apoptosis induction in mouse embryonic cellsas a pregnane X receptor (PXR) in porcine brain capillary endothelial cells for transport assay
Biochem/physiol Actions
Hyperforin is an active antidepressant and an inhibitor of cytochrome P450 3A4 (CYP3A). It elicits antioxidant and antibacterial activity. Hyperforin is also embryotoxic and inhibits tumor proliferation. It effectively inhibits dopamine, serotonin and norepinephrine.
General description
Hyperforin is a phloroglucinol component of St. John′s wort and a pregnane X receptor ligand.
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :