Bromure d'hexaméthonium,

Code: h0879-25g D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Hexamethonium bromide has been used:as an autonomic ganglia-blocking agent to study its effects on whisker movement in ratsas a nicotinic receptor antagonist to s...


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$73.37 25G
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Hexamethonium bromide has been used:as an autonomic ganglia-blocking agent to study its effects on whisker movement in ratsas a nicotinic receptor antagonist to study its effects on antigen-induced arthritis (AIA) progression in miceas a non-selective ganglionic nicotinic acetylcholine receptor (nAChR) antagonist to study its effects on cytisine-induced autonomic cardiovascular responses in mice

Biochem/physiol Actions

Hexamethonium bromide is a nicotinic acetylcholine receptor (nAChR) antagonist. It preferentially blocks nicotinic receptors at autonomic ganglia. It can cross the blood-brain barrier only at high doses.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Gene Informationhuman ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)
InChI keyFAPSXSAPXXJTOU-UHFFFAOYSA-L
InChI1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
mp282-285 °C (dec.)
Quality Level200
SMILES string[Br-].[Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C
Cas Number55-97-0
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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