GR 32191B, >=98% (HPLC), solid

Name: GR 32191B, >=98% (HPLC), solid
Brand: SIGMA-ALDRICH
SKU: G5044-1MG
Price: 216.74 USD

Code: G5044-1MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Selective TP prostanoid receptor antagonist. Inhibits U-46619-induced contraction of guinea pig trachea with IC₅₀=1.8 nM.

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Not available outside of the UK & Ireland.
Biochem/physiol Actions
Selective TP prostanoid receptor antagonist. Inhibits U-46619-induced contraction of guinea pig trachea with IC₅₀=1.8 nM.
Features and Benefits
This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information
Manufactured and sold under agreement from GlaxoSmithKline
Packaging
1, 5 mg in glass bottle

assay ≥98% (HPLC)
color off-white
form solid
InChI key ZYOBZRTZRQKKNC-UGNABIHOSA-N
InChI 1S/C30H39NO4.ClH/c32-27-21-28(35-22-23-15-17-25(18-16-23)24-11-5-3-6-12-24)26(13-7-1-2-8-14-29(33)34)30(27)31-19-9-4-10-20-31;/h1-3,5-6,11-12,15-18,26-28,30,32H,4,7-10,13-14,19-22H2,(H,33,34);1H/b2-1-;/t26-,27-,28-,30+;/m0./s1
mp 127-128 °C
originator GlaxoSmithKline
Quality Level 100
shipped in wet ice
SMILES string Cl.O[C@H]1C[C@H](OCc2ccc(cc2)-c3ccccc3)[C@H](CCC=C/CCC(O)=O)[C@H]1N4CCCCC4
solubility H₂O: ~16 mg/mL
storage temp. −20°C

Safety Data Sheet
Safety Data Sheet for G5044-1MG
Certificate of Analysis
Sigma Certificate of Analysis

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Cas Number 87248-13-3

This product has met the following criteria to qualify for the following awards:

GR 32191B, >=98% (HPLC), solid

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assay	≥98% (HPLC)
color	off-white
form	solid
InChI key	ZYOBZRTZRQKKNC-UGNABIHOSA-N
InChI	1S/C30H39NO4.ClH/c32-27-21-28(35-22-23-15-17-25(18-16-23)24-11-5-3-6-12-24)26(13-7-1-2-8-14-29(33)34)30(27)31-19-9-4-10-20-31;/h1-3,5-6,11-12,15-18,26-28,30,32H,4,7-10,13-14,19-22H2,(H,33,34);1H/b2-1-;/t26-,27-,28-,30+;/m0./s1
mp	127-128 °C
originator	GlaxoSmithKline
Quality Level	100
shipped in	wet ice
SMILES string	Cl.O[C@H]1C[C@H](OCc2ccc(cc2)-c3ccccc3)[C@H](CCC=C/CCC(O)=O)[C@H]1N4CCCCC4
solubility	H₂O: ~16 mg/mL
storage temp.	−20°C