Fumagillin from Aspergillus fumigatus, >=90%, powder

Code: F6771-5MG D2-231

Not available outside of the UK & Ireland.

Application

Fumagillin from Aspergillus fumigatus has been used:in chick chorioallantoic membrane (CAM) assay to study the changes in protein expression in response ...


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$1,328.70 5MG
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Not available outside of the UK & Ireland.

Application

Fumagillin from Aspergillus fumigatus has been used:in chick chorioallantoic membrane (CAM) assay to study the changes in protein expression in response to anti-angiogenic agentto study its effects on the mortality of caged Nosema ceranae-infected honey bees- write in this way as a positive control in in vitro and ex vivo studies

Biochem/physiol Actions

Fumagillin is known to be effective against microsporidian fungal infections.

Methionine aminopeptidase-2 (MetAP-2) inhibitor; inhibits endothelial cell proliferation and angiogenesis.

General description

Fumagillin is a metabolic product of fungi. It is originally isolated from Aspergillus fumigatus.

Packaging

1, 5 mg in serum bottle

antibiotic activity spectrumfungi
assay≥90%
biological sourceAspergillus sp. (Aspergillus fumigatus)
colorwhite
formpowder
InChI keyNGGMYCMLYOUNGM-HCNIIHBUSA-N
InChI1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+
mode of actionDNA synthesis | interferes
mp197-198 °C
Quality Level200
SMILES stringCOC1C(CCC2(CO2)C1C3(C)OC3CC=C(C)C)OC(=O)C=CC=CC=CC=CC(O)=O
solubilityethanol: 1 mg/mL
storage temp.−20°C
Cas Number23110-15-8
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