DCB, >=98% (HPLC), solid

Code: D1068-50MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Neutral allosteric modulator of the metabotropic glutamate receptor mGluR5.

3,3′-dichlorobenzaldazine (DCB) serves as an allosteric l...


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$360.78 50MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Neutral allosteric modulator of the metabotropic glutamate receptor mGluR5.

3,3′-dichlorobenzaldazine (DCB) serves as an allosteric ligand with neutral cooperativity. It helps to block the positive allosteric regulation of mGluRs (metabotropic glutamate receptor subtype 5 (mGluR5) with the help of 3,3′-difluorobenzaldazine (DFB) and the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB).

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
coloryellow
formsolid
InChI keyXMOVWXSCYLINBJ-BEQMOXJMSA-N
InChI1S/C14H10Cl2N2/c15-13-5-1-3-11(7-13)9-17-18-10-12-4-2-6-14(16)8-12/h1-10H/b17-9+,18-10+
Quality Level100
SMILES stringClc1cccc(C=NN=Cc2cccc(Cl)c2)c1
solubilityDMSO: ~6.8 mg/mL, H2O: insoluble
storage conditiondesiccated, under inert gas
storage temp.2-8°C
Cas Number6971-97-7
This product has met the following criteria to qualify for the following awards:



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