Dihydrokainic acid, >=98% (HPLC), powder

Code: D1064-50MG D2-231

Not available outside of the UK & Ireland.

Application

Dihydrokainic acid has been used as a glutamate transporter (GLT-1) inhibitor in the glutamate uptake assay of astrocytes and glial cells. It may be used as a GLT...


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Your Price
$1,027.15 50MG
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Not available outside of the UK & Ireland.

Application

Dihydrokainic acid has been used as a glutamate transporter (GLT-1) inhibitor in the glutamate uptake assay of astrocytes and glial cells. It may be used as a GLT-1 inhibitor in Lateral habenula (LHb).

Biochem/physiol Actions

Dihydrokainic acid is a selective inhibitor of the GLT-1 glutamate transporter. At higher concentrations, dihydrokainate is a weak inhibitor of AMPA/kainate glutamic acid receptors.

Dihydrokainic favors neuronal cell death. It modulates anxiety and depression behaviors.

Features and Benefits

This compound is featured on the Excitatory Amino Acid Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
formpowder
Gene Informationhuman ... SLC1A1(6505), SLC1A2(6506), SLC1A3(6507)rat ... Slc1a2(29482), Slc1a3(29483)
InChI keyJQPDCKOQOOQUSC-OOZYFLPDSA-N
InChI1S/C10H17NO4/c1-5(2)7-4-11-9(10(14)15)6(7)3-8(12)13/h5-7,9,11H,3-4H2,1-2H3,(H,12,13)(H,14,15)/t6-,7+,9-/m0/s1
Quality Level100
SMILES stringCC(C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O
solubilityH2O: >10 mg/mL
storage temp.2-8°C
Cas Number52497-36-6
This product has met the following criteria to qualify for the following awards:



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