Calphostin C from Cladosporium cladosporioides, >=90% (HPLC), powder

Code: C6303-1MG D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Highly specific inhibitor of protein kinase C (IC50 = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), ...


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$2,355.85 1MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

Highly specific inhibitor of protein kinase C (IC50 = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.

Features and Benefits

This compound is featured on the Phospholipase D and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

assay≥90% (HPLC)
biological sourcemicrobial (Cladosporium cladosporioides)
colorred to brown
formpowder
InChI keySRJYZPCBWDVSGO-UHFFFAOYSA-N
InChI1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3
Quality Level200
SMILES stringCOc1cc(O)c2C(=O)C(OC)=C(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5C(CC(C)OC(=O)c6ccccc6)=C(OC)C(=O)c7c(O)cc(OC)c(c57)c1c24
solubilityethanol: 1 mg/mL, DMSO: 1 mg/mL, DMF: 1 mg/mL
storage temp.−20°C
Cas Number121263-19-2
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