Not available outside of the UK & Ireland.
Biochem/physiol Actions
HRSP12 (Heat-responsive protein 12) mainly acts as a translational inhibitor protein. It has been proposed that the protein may have the potentiality to perform in various cellular mechanisms such as a differentiation-dependent regulation of protein synthesis in hepatocytes, renal tubular epithelial cells, smooth muscle cells and mononuclear phagocytes (MNP).
General description
HRSP12 (Heat-responsive protein 12) is a trichloroacetic acid soluble protein belonging to the hypothetical family of small proteins, termed as YER057c/YJGF family. It has a molecular weight of 14.5kDa. It is expressed in monocytes, liver and kidney tumor cells. Its high level of expression has been reported in fully differentiated monocytes.
Immunogen
HRSP12 (AAH10280.1, 1 a.a. ~ 137 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.SequenceMSSLIRRVISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLVSGGVAEEAKQALKNMGEILKAAGCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAIQGPLTTASL
Legal Information
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Physical form
Solution in phosphate buffered saline, pH 7.4
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