Monoclonal Anti-EBV antigen EBNA-1 antibody produced in mouse, clone E1-2.5, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Epstein–Barr nuclear antigen 1 (EBNA-1) plays an essential role in the replication of the Epstein-Barr virus (EBV) genome as an extrachromosomal element. In addition, it also regulates transcription of a EBV latent gene expression. EBNA-1 is essential for maintenance of EBV in episomal form.

Disclaimer

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Features and Benefits

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General description

The antibody E1-2.5 recognizes repetitive Gly-Ala region of the Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1). EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

Immunogen

EBNA-1

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.