Monoclonal Anti-HLA-DR1 antibody produced in rat, clone MEM-267, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Suggested working dilution for immunoblotting is 1-5 µg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

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General description

The antibody MEM-267 specifically binds to the empty but not peptide-loaded form of HLA-DR1. DR is the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).

Immunogen

Purified, insoluble DR1 beta chain (DRB1*0101) expressed in E. coli inclusion bodies

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.