Monoclonal Anti-HLA-A azide free antibody produced in mouse, clone BB7.2, purified immunoglobulin, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 5-10 µg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Biochem/physiol Actions

Human leukocyte antigen A α-chain (HLA-A2) plays a major role in peptide antigen presentation. The encoded protein interacts with cytotoxic T cells (CTL) and facilitates the identification of peptide derived from the influenza matrix protein.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

The antibody BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn on one of the underlying beta strands within the human HLA-A2 histocompatibility antigen.

Human leukocyte antigen A α-chain (HLA-A2) is encoded by the gene mapped to human chromosome 6p22.1. HLA-A belongs to the class I molecules of HLa family. The protein structure consists of two polypeptide chains, heavy chain and the non-covalently attached light chain.

Immunogen

HLA-A2 solubilized by papain

Physical form

Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized.