Anti-phospho-AXL (pTyr691) antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

AXL (receptor tyrosine kinase) controls innate immune responses. It participates in cellular transformation and tumor progression. Overexpression of AXL is characterized with higher liability for lymphatic metastases.

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General description

AXL (receptor tyrosine kinase) is also termed as Ark, UFO or Tyro7. This gene is overexpressed in pancreatic cancer tissues. AXL belongs to the receptor tyrosine kinase family. It is obtained as a transforming gene from human leukemia cells. AXL is mapped to human chromosome 19q13.

Immunogen

The antiserum was produced against synthesized peptide derived from human AXL around the phosphorylation site of Tyr691.Immunogen Range: 657-706

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.