Anti-phospho-PLK1 (pThr210) antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Polo-like kinase 1 (PLK1) plays an important role in the functional maturation of mitotic centrosomes. It actively participates in the development of the cell cycle. This gene is considered as an important therapeutic target as it is overexpressed in several cancer types.

Features and Benefits

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General description

Human polo-like kinase 1 (PLK1) is a serine/threonine kinase, that is located on human chromosome 16p12.

Immunogen

The antiserum was produced against synthesized peptide derived from human PLK1 around the phosphorylation site of Thr210.Immunogen Range: 176-225

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.