Anti-CD40, C-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Application

Anti-CD40, C-Terminal antibody has been used in western blotting.

Biochem/physiol Actions

Cluster of differentiation 40 (CD40) plays a major role in cellular and humoral immunity. It initiates inflammatory response to induce the progression of atherosclerosis.The CD40 pathway participates in the growth and pathogenesis of autoimmune diseases like rheumatoid arthritis (RA).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Cluster of differentiation 40 (CD40) is a type I transmembrane glycoprotein. It has a molecular weight of 40 ~ 50kDa and made of 277 amino acids. The CD40 gene is mapped to human chromosome 20q11-13. It has eight introns and nine exons.

Anti-CD40 Antibody detects endogenous levels of total CD40 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human CD40.Immunogen Range: 228-277

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.