Anti-USP44 antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

USP44 (ubiquitin-specific protease 44) plays a major role in the mitotic checkpoint. Absence of USP44 leads to chromosome mis-segregation, aneuploidy and tumorigenesis in vivo.

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Features and Benefits

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General description

Anti-USP44 Antibody detects endogenous levels of total USP44 protein.

USP44 (ubiquitin-specific protease 44) codes for a 712 amino acid protein. It belongs to the ubiquitin-specific protease (USP) family. USP44 contains a ZnF-UBP (zinc-finger ubiquitin-specific protease) domain and conserved cysteine, histidine and asparagine/aspartic acid residues.It is abundantly expressed in the nucleus. It is mapped to human chromosome 12q22.

Immunogen

The antiserum was produced against synthesized peptide derived from human USP44.Immunogen Range: 211-260

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.