Not available outside of the UK & Ireland.
Biochem/physiol Actions
SFRP2 (secreted frizzled related protein 2) promotes phosphorylation and retards the expression of nuclear β-catenin and inhibits the canonical Wnt signaling pathway. SFRP2 is known to enhance osteogenic differentiation in mesenchymal stem cells.
Features and Benefits
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General description
The SFRP2 (secreted frizzled related protein 2) gene is mapped to human chromosome 4q31.3. It is found to be expressed in sclerotome.
Anti-SFRP2 Antibody detects endogenous levels of total SFRP2 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human SFRP2.Immunogen Range: 119-168
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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