Anti-KCNJ5, C-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

KCNJ5 (potassium voltage-gated channel subfamily J member 5) is associated with aldosteronism, a major cause of secondary hypertension. Mutated KCNJ5 gene affects the polarization of plasma membrane and permit sodium and calcium inflow into the cells.

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General description

Anti-KCNJ5 Antibody detects endogenous levels of total KCNJ5 protein.KCNJ5 (potassium voltage-gated channel subfamily J member 5) is an inwardly rectifying potassium channel, which is also termed as GIRK4 (G protein-coupled inward rectifier K⁺ channel 4). It is expressed in the cerebral cortex. This gene is mapped to human chromosome 11q24.

Immunogen

The antiserum was produced against synthesized peptide derived from human KCNJ5.Immunogen Range: 370-419

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.