Non disponible en dehors du Royaume-Uni et de l'Irlande
Biochem/physiol Actions
Mutations in ITGB3 (integrin subunit β 3) results in Glanzmann thrombasthenia (GT). It plays a major role in the movement and attack of colorectal cancer cells promoted by reactive oxygen species.
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General description
ITGB3 (integrin subunit β 3) codes for integrin αIIbβ3. It is located on human chromosome 17q21.31-32.
Anti-Integrin β3 Antibody detects endogenous levels of total Integrin β3 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human Integrin beta3.Immunogen Range: 739-788
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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