Anti-IRS-1 antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Not available outside of the UK & Ireland.

Biochem/physiol Actions

Insulin receptor substrate 1 (IRS1) participates in the insulin signaling pathway. It is associated with type 2 diabetes (T2D). IRS1 regulates glucose homeostasis, body growth and peripheral insulin action.

Features and Benefits

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General description

Anti-IRS-1 Antibody detects endogenous levels of total IRS-1 protein.

Insulin receptor substrate 1 (IRS1) belongs to the IRS family. It is mapped to human chromosome 2q36.

Immunogen

The antiserum was produced against synthesized peptide derived from human IRS-1.Immunogen Range: 289-338

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.